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SpatialEx

The source code for "High-Parameter Spatial Multi-Omics through Histology-Anchored Integration".

Our step-by-step tutorial can be found here.

Overall architecture of SpatialEx and SpatialEx+

Usage

You can run the following the command.

pip install requirements.txt
pip install SpatialEx

We have packaged our implementation into an easy-to-use Python library for use by the research community. The accompanying tutorial offers detailed guidance on how to use the package effectively.

A detailed guide to all applications in the paper is available in Demonstration.ipynb.

Prepare datasets

The Xenium Human Breast Cancer tissue dataset is available at this site.

The 10x Xenium Human Breast Using the Entire Sample Area dataset is publicly available at this site.

The Visium Spatial Multimodal Analysis (SMA) dataset is available at this site.

If you have any questions, please feel free to contact us via email.

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The source code for "High-Parameter Spatial Multi-Omics through Histology-Anchored Integration"

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